Kirigami-Inspired Brain Implant Captures Neural Signals with Unmatched Flexibility

Scientists have created a flexible microelectrode array inspired by kirigami, the Japanese art of paper cutting. The device is designed for long-term, large-scale recordings of brain activity in primates. Early tests show it can capture detailed neural signals while adapting to the brain's natural movements.

The new array uses a reconfigurable spiral thread design that moulds itself to the brain's surface. Unlike rigid implants, it stretches and bends without losing electrical function or peeling away from the tissue. This flexibility prevents inflammation and scarring, which often occur when stiff devices rub against the brain.

The array is placed on the brain using a water-dissolvable carrier coated in hydrogel. This method minimises damage during insertion. Once in place, the device moves with the brain, accommodating tiny shifts caused by breathing, heartbeat, and head movements.

In trials with macaque monkeys, the array recorded signals from over 700 individual neurons at once. The high-quality data allowed researchers to decode upper-limb movements with precision. This suggests potential for future brain-machine interfaces that could restore mobility or control prosthetics.

The design also solves a key problem: the mismatch between hard electronics and soft brain tissue. By covering large areas without fixed anchor points, it avoids the limitations of older, smaller devices.

The kirigami-inspired array offers a less invasive way to monitor brain activity over time. Its ability to move with the brain while capturing detailed neural data could improve neuroprosthetics and other medical technologies. Further testing will determine its long-term reliability and broader applications.